Malignant transformation of hamster kidney cells by BK virus.

Electron microscopic features of a brain tumor induced in hamster by BK virus, a human papova virus.

In order to locate the target cells for malignant transformation by BK virus (a human papova virus) in hamster brain, electron microscopic observation of tumor originally induced in hamster brain by BK virus was performed. With light microscopy, the BK virus-induced tumor (Vn 17) bore a close resemblance to human malignant ependymoma. Under the electron microscope, numerous microvilli and few c...

Decreasing the number of 68-base-pair tandem repeats in the BK virus transcriptional control region reduces plaque size and enhances transforming capacity.

Wild-type BK virus, which has three 68-base-pair (bp) elements tandemly repeated in its transcriptional control region, forms clear, large plaques in human embryonic kidney cell cultures but rarely transforms hamster or rat cells. From this BK virus DNA, deletion mutants with fewer than three 68-bp elements were constructed and characterized. The mutant DNA with two 68-bp elements formed small,...

بررسی مولکولی فعالیت مجدد ویروس BK در ادرار بیماران پیوند کلیه

  Background & Amis: BK polyomavirus (BKV) is common infection of childhood that persists in kidney epithelium. BKV reactivation characterized by viruria occurs in 35% to 57% of renal allograft recipients. BK virus was detected in serum samples in 6% to 29% of these patients.  BKV-associated nephropathy occurs in as many as 8% of renal allograft recipients and may lead to . This study was carri...

Comparative attenuation of African horsesickness virus in mosquito (Aêdes albopictus) and in hamster kidney (BHK-21) celllines

Evaluating of Iran Razi Khedmati Bovine Kidney (IRKHBK) Cell Line for Isolation and ‎Propagation of Viruses

Abstract Background and Aims: To identify and isolation of viruses a susceptible cell is need which can be primary or line. The use of primary cells is laborious, time consuming and expensive, while the use of cell lines is much easier and faster. IRKHBK cell line was originated from primary cells of bovine kidney by continuous passage. The aim of this study was to introduce the IRKHBK cell ...